Biology Direct serves the life science research community as an open access, peer-reviewed online journal, providing authors and readers with an alternative to the traditional model of peer review. Biology Direct considers original research articles, hypotheses, comments, discovery notes and reviews in selected subject areas, and will eventually cover the full spectrum of biology.
Subject areas already launched include:
- Genomics, Bioinformatics and Systems Biology - Edited by Eugene Koonin, Laura Landweber, & David Lipman.
- Immunology - Edited by Neil S Greenspan & David R Kaplan.
- Mathematical Biology - Edited by Marek Kimmel.
Editors-in-Chief
- Eugene Koonin, NCBI, NLM, NIH
- Laura Landweber, Princeton University
- David Lipman, NCBI, NLM, NIH
Articles
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Research
Biology Direct 2012, 7:16 (8 May 2012)Increased burst size in multiply infected cells can alter basic virus dynamics
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Discovery notes
Biology Direct 2012, 7:15 (8 May 2012)On the complexity of miRNA-mediated regulation in plants: novel insights into the genomic organization of plant miRNAs
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Research
Biology Direct 2012, 7:14 (8 May 2012)Structure based hypothesis of a mitochondrial ribosome rescue mechanism
Modeling the 3D structure of the human protein mtRF1 shows that it likely functions in recognizing and recycling stalled mitochondrial ribosomes. -
Research
Biology Direct 2012, 7:13 (19 April 2012)A novel virus genome discovered in an extreme environment suggests recombination between unrelated groups of RNA and DNA viruses
The discovery of a previously unknown viral genome, the apparent result of a recombination event between unrelated RNA and DNA viruses, has implications for theories of viral evolution. -
DELTA-BLAST is a new BLAST alignment tool for sensitive protein searches that uses conserved domain models to construct a position specific scoring matrix.
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Probable ancestors of eukaryotic tubulins, denoted artubulins, were discovered in two genomes of thaumarchaeota of the genus Nitrosoarchaeum.
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Research
Biology Direct 2012, 7:9 (21 February 2012)Reaction-Diffusion-Delay Model for EPO/TNF-alpha Interaction in Articular Cartilage Lesion Abatement
Graham et al. present a mathematical model that connects the biochemical interactions of cartilage cells with the spatial behavior observed in cartilage injury. -
Research
Biology Direct 2012, 7:8 (15 February 2012)Rate and breadth of protein evolution are only weakly correlated
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Research
Biology Direct 2012, 7:7 (13 February 2012)The CMG (CDC45/RecJ, MCM, GINS) complex is a conserved component of the DNA replication system in all archaea and eukaryotes
Comparative genomic analysis reveals diverged orthologs of eukaryotic CDC45 protein and bacterial RecJ nuclease in nearly all archaeal genomes; the CMG complex is conserved in both archaea and eukaryotes, and appears to be an essential component of the ancestral DNA replication machinery. - View more articles
Unique model of peer review
Biology Direct offers a novel system of peer review, allowing authors to select suitable reviewers from the journal's Editorial Board; making the peer-review process open rather than anonymous; and making the reviewers' reports public, thus increasing the responsibility of the referees and eliminating sources of abuse in the refereeing process.
Thematic series
Beyond the tree of life
Edited by Dr Maureen O'Malley and Dr Yan Boucher
Published: 30 June 2011
Evolution and cancer: A mathematical biology approach
Edited by Prof Marek Kimmel
Published: 20 April 2010
Evolutionary Biology 150 years after the 'Origin': is a post-modern synthesis in sight?
Edited by Dr Eugene Koonin
Published: 24 April 2009
Origin and early evolution of life
Edited by Dr Eugene Koonin
Published: 9 July 2008
View all article series
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Indexed by
- BIOSIS
- CAS
- Embase
- EmBiology
- MEDLINE
- PubMed
- PubMed Central
- Science Citation Index Expanded
- Scopus
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