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One ancestor for two codes viewed from the perspective of two complementary modes of tRNA aminoacylation
Andrei S Rodin, Eörs Szathmáry, Sergei N Rodin Biology Direct 2009, 4:4 (27 January 2009)
Abstract | Full text | PDF
| PubMed | Cited on BioMed Central
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Editor’s summary
The genetic code mediated in tRNAs by anticodons and the code embodied in tRNA acceptor stems responsible for correct tRNA aminoacylation have one common ancestor, originating even before translation.
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A DNA topoisomerase IB in Thaumarchaeota testifies for the presence of this enzyme in the last common ancestor of Archaea and Eucarya
Céline Brochier-Armanet, Simonetta Gribaldo, Patrick Forterre Biology Direct 2008, 3:54 (23 December 2008)
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| PubMed | Cited on BioMed Central
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Evidence from glycine transfer RNA of a frozen accident at the dawn of the genetic code
Harold S Bernhardt, Warren P Tate Biology Direct 2008, 3:53 (17 December 2008)
Abstract | Full text | PDF
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Editor’s summary
We present evidence the first tRNA was specific for glycine, with an NCC anticodon derived from the 3'-CCA of a duplicated hairpin precursor, heralding the dawn of the genetic code.
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An extension of the coevolution theory of the origin of the genetic code
Massimo Di Giulio Biology Direct 2008, 3:37 (5 September 2008)
Abstract | Full text | PDF
| PubMed | Cited on BioMed Central
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Editor’s summary
A modification of the coevolution theory of the origin of the genetic code suggesting that the biosynthetic pathways of amino acids imprinted the genetic code organization early on.
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The evolution of strand preference in simulated RNA replicators with strand displacement: Implications for the origin of transcription
Nobuto Takeuchi, Laura Salazar, Anthony M Poole, Paulien Hogeweg Biology Direct 2008, 3:33 (11 August 2008)
Abstract | Full text | PDF
| PubMed | Cited on BioMed Central
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Editor’s summary
Finite diffusion is shown to enable the evolution of a transcription-like pattern in a simple RNA-based replicator system with strand displacement
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The Last Universal Common Ancestor: emergence, constitution and genetic legacy of an elusive forerunner
Nicolas Glansdorff, Ying Xu, Bernard Labedan Biology Direct 2008, 3:29 (9 July 2008)
Abstract | Full text | PDF
| PubMed | Cited on BioMed Central
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Editor’s summary
The Last Universal Common Ancestor developed in a protoeukaryotic, promiscuous and genetically redundant community of cells with a broad, moderate thermal profile and an RNA genome enclosed in a protonucleus.
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