http://www.biology-direct.com/content/4/1/28/comments The latest comments on the article 'On the need for widespread horizontal gene transfers under genome size constraint' 2009-09-24T10:33:42Z http://www.biology-direct.com/content/4/1/28/comments#368661 <p>In 2003, Ford Doolittle called this the "Genome of Eden" constraint, in Phil Trans Roy Soc Lond B. In 2007 (PNAS) and 2008 (PNAS), Tal Dagan used it to estimate LGT frequency and cumulative impact among prokaryotes. Good idea, again. </p> William Martin 2009-09-24T10:33:42Z http://www.biology-direct.com/content/4/1/28 Isambert et al. Biology Direct 4 28 Tue Aug 25 08:28:51 BST 2009