http://www.biology-direct.com/content/3/1/4/comments The latest comments on the article 'Orphan SelD proteins and selenium-dependent molybdenum hydroxylases' 2008-03-10T10:59:58Z http://www.biology-direct.com/content/3/1/4/comments#296568 <p>To access the above referenced article please <a href='http://genomebiology.com/2006/7/10/R94'>click here</a>.</p> Andrea Melendez 2008-03-10T10:59:58Z http://www.biology-direct.com/content/3/1/4 Haft et al. Biology Direct 3 4 Wed Feb 20 14:53:11 GMT 2008 http://www.biology-direct.com/content/3/1/4/comments#294573 <p>Just after publication of our manuscript, we came across the following reference: Zhang Y, Romero H, Salinas G, Gladyshev VN., Dynamic evolution of selenocysteine utilization in bacteria: a balance between selenoprotein loss and evolution of selenocysteine from redox active cysteine residues. Genome Biol. 2006;7(10):R94. Epub 2006 Oct 20. We launched our study from the observation that SelD proteins explained by neither selenocysteine nor selenouridine pathways might imply a third SelD-dependent trait. The orphan status of SelD in Enterococcus faecalis and Haloarcula marismortui and possibility of SelD-dependence for selenium-dependent molybdenum hydroxylases were raised previously by Zhang, et al., and should have been cited as background to this paper. We regret having been unaware of this earlier observation.</p> Daniel Haft 2008-03-04T10:24:46Z http://www.biology-direct.com/content/3/1/4 Haft et al. Biology Direct 3 4 Wed Feb 20 14:53:11 GMT 2008