Editors-in-Chief: Eugene V Koonin, National Center for Biotechnology Information, NIH; Laura F Landweber, Princeton University; David J Lipman, National Center Biotechnology Information, NIH
Biology Direct considers original research articles, hypotheses, comments, discovery notes and reviews in selected subject areas, and will eventually cover the full spectrum of biology.
Subject areas already launched include:
- Genomics, Bioinformatics and Systems Biology - Edited by Eugene Koonin, Laura Landweber, & David Lipman
- Immunology - Edited by Neil S Greenspan & David R Kaplan
- Mathematical Biology - Edited by Marek Kimmel.
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To commemorate the 200th anniversary of Charles Darwin's birth and the 150th anniversary of the publication of the "Origin of Species", Biology Direct has published the first articles in a thematic series dedicated to the current state of evolutionary biology, under the general heading
"Evolutionary Biology 150 years after the 'Origin': is a post-modern synthesis in sight?"
The series consists of critical reviews, discussion and original research articles that investigate and assess today's understanding of evolution at all levels, the fate of the legacy of Darwin and the Modern Synthesis, and the goals and prospects for the next half-century.
Latest articles

Hypothesis
 Some considerations for analyzing biodiversity using integrative metagenomics and gene networks Lucie Bittner, Sebastien Halary, Claude Payri, Corinne Cruaud, Bruno de Reviers, Philippe Lopez, Eric Bapteste Biology Direct 2010, 5:47 (30 July 2010) [Abstract] [Provisional PDF]
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Theoretical considerations on metagenomics and DNA barcoding suggest that evolutionary gene networks, a novel inclusive integrative network-based approach, could improve biodiversity estimates of the elements, functions and evolutionary processes present in the environments.
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Research
 The evolutionary rate variation among genes of HOG-signaling pathway in yeast genomes Xuechang Wu, Xiaoqin Chi, Pingmei Wang, Daoqiong Zheng, Rui Ding, Yudong Li Biology Direct 2010, 5:46 (10 July 2010) [Abstract] [Provisional PDF] [PubMed] [Related articles]
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The evolutionary rates of genes in HOG-signaling pathway varied greatly across yeast species, and could be affected by functional constraints, pathway position, and other factors.
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Comment
 Opportunities and challenges for digital morphology Alexander Ziegler, Malte Ogurreck, Thomas Steinke, Felix Beckmann, Steffen Prohaska, Andreas Ziegler Biology Direct 2010, 5:45 (6 July 2010) [Abstract] [Full Text] [PDF] [PubMed] [Related articles]
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Research
  Save the tree of life or get lost in the woods Ruben E Valas, Philip E Bourne Biology Direct 2010, 5:44 (1 July 2010) [Abstract] [Full Text] [PDF] [PubMed] [Related articles]
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Discovery notes
 Presence of a classical RRM-fold palm domain in Thg1-type 3'- 5'nucleic acid polymerases and the origin of the GGDEF and CRISPR polymerase domains Vivek Anantharaman, Lakshminarayan M Iyer, L Aravind Biology Direct 2010, 5:43 (30 June 2010) [Abstract] [Full Text] [PDF] [PubMed] [Related articles]
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