Figure 6.

Linear correlation between genome size and GC content. Bacterial genome sizes are represented by the number of genes. Bacteria with less than 2,500 genes were chosen for analysis in dnaE1|polV (A) and dnaE3|polV (B), respectively. There is a strong and significant correlation between genome size and GC content after eliminating outliers (red solid circles). R values change from 0.6179 to 0.7479 (p < 0.0001) in the dnaE1|polV group and from 0.5571 to 0.8172 (p < 0.0001) in the dnaE3|polV group. The linear model is Y = 0.0001128X + 0.2387 for the dnaE1|polV group and Y = 0.00006374X + 0.2464 for the dnaE3|polV group. 90% upper and lower prediction limits are also shown. All the numbered outliers were further analyzed to interpret potential reasons underlying this correlation (Table 6).