Research
Purine biosynthesis in archaea: variations on a theme
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* Corresponding author: Catherine A Sarisky Sarisky@roanoke.edu
1 Department of Chemistry, Roanoke College, Salem, VA 24153, USA
2 Department of Biochemistry, Virginia Polytechnic Institute and State University, Blacksburg, VA 24061-0308, USA
3 Department of Cell and Molecular Physiology, University of North Carolina at Chapel Hill, School of Medicine, Chapel Hill, NC 27599, USA
Biology Direct 2011, 6:63 doi:10.1186/1745-6150-6-63
Published: 14 December 2011Additional files
Additional file 1:
Spreadsheet with gene locus tags for all purine biosynthesizing genes identified. This Excel spreadsheet contains full organism names and taxonomies, IMG taxon IDs, and gene locus tags for all purine biosynthesizing genes identified, corresponding to the locus tags available in IMG. Locus tags are in parentheses when significant features (such as expected active site residues or expected domains) are absent from the predicted protein. The designation "PurH1" is used for the typically C-terminal AICAR formyltransferase domain, while the designation "PurH2" is used for the typically N-terminal IMP cyclohydrolase domain of full-length PurH. For other predicted proteins, the locus tags were separated by a + when two adjacent ORFs appeared to each encode part of full-length expected protein. The designations "(in purL)" and "(in purE)" were used to denote cases where the expected function appeared to be provided by the PurL or PurE protein, as described further in the text.
Format: XLSX Size: 23KB Download file
Additional file 2:
Zip file containing additional phylogenetic trees. A set of phylogenetic trees generated as described in the Methods section. Locus tags were used for archaeal proteins, while species names were used for non-archaeal proteins used for comparisons.
Format: ZIP Size: 74KB Download file