Research
Transcription factor binding sites are highly enriched within microRNA precursor sequences
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* Corresponding author: Neil R Smalheiser neils@uic.edu
1 Genome Institute, National Center for Genetic Engineering and Biotechnology, 113 Thailand Science Park, Klong1, Klong Luang, Pathumthani 12120, Thailand
2 School of Biology, Georgia Institute of Technology, Atlanta, Georgia 30332 USA
3 Department of Bioengineering, University of Illinois at Chicago, Chicago, Illinois, USA
4 Department of Psychiatry, University of Illinois at Chicago, UIC Psychiatric Institute MC912, 1601 W. Taylor Street, Chicago, IL 60612 USA
Biology Direct 2011, 6:61 doi:10.1186/1745-6150-6-61
Published: 2 December 2011Additional files
Additional file 1:
Spreadsheet containing a list of all human pre-miRs that contain high-confidence conserved TFBS motifs (z-score ≥ 2.33) (sheet 1) and a list of TRANSFAC transcription factors that bind these TFBS motifs (sheet 2).
Format: XLSX Size: 25KB Download file
Additional file 2:
File showing the location of each high-confidence conserved TFBS (z-score ≥ 2.33) on each pre-miR sequence. Positions of miRBase-annotated mature miRNA sequences (OOOO....) and miRNA* sequences (NNNNN....) are indicated within each pre-miR.
Format: TXT Size: 70KB Download file