Research
Not all transmembrane helices are born equal: Towards the extension of the sequence homology concept to membrane proteins
-
* Corresponding author: Frank Eisenhaber franke@bii.a-star.edu.sg
1 Bioinformatics Institute (BII), Agency for Science, Technology and Research (A*STAR), 30 Biopolis Street, #07-01, Matrix, 138671 Singapore
2 School of Biological Sciences (SBS), Nanyang Technological University (NTU), 60 Nanyang Drive, 637551 Singapore
3 Department of Biological Sciences (DBS), National University of Singapore (NUS), 8 Medical Drive, 117597 Singapore
4 School of Computer Engineering (SCE), Nanyang Technological University (NTU), 50 Nanyang Drive, 637553 Singapore
Biology Direct 2011, 6:57 doi:10.1186/1745-6150-6-57
Published: 25 October 2011Additional files
Additional file 1:
Supplementary Table 1. This table contains the statistically-enriched residues in the anchor sets (membrane/signal) and functional TM-helix sets (UniProt/SCOP-derived) when tested against each other through 2-by-2 contingency tables.
Format: PDF Size: 110KB Download file
This file can be viewed with: Adobe Acrobat Reader
Additional file 2:
Supplementary Table 2. This table contains the correlation values between the four sets of statistically-enriched residues derived from Additional file 1, Supplementary Table 1 and a set of experimentally-derived hydrophobicity scale.
Format: PDF Size: 21KB Download file
This file can be viewed with: Adobe Acrobat Reader