Biology Direct

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Including RNA secondary structures improves accuracy and robustness in reconstruction of phylogenetic trees

Alexander Keller, Frank Förster, Tobias Müller, Thomas Dandekar, Jörg Schultz* and Matthias Wolf*

Author Affiliations

Department of Bioinformatics, University of Würzburg, Am Hubland, 97074 Würzburg, Germany

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Biology Direct 2010, 5:4 doi:10.1186/1745-6150-5-4

Published: 15 January 2010

Additional files

Additional file 1:

Normalized Quartet distance and Robinson-Foulds plots. Similar to Figures 2 and 4, but showing per-branch Quartet distances as a normalized standard i.e. divided by number of splits. Robinson-Foulds Distances are given in absolute and normalized versions.

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Additional file 2:

Empirical pairwise distances. Pairwise distances of an ITS2 case study that integrates secondary structure.

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Additional file 3:

Substitution matrices. Nucleotide 4 × 4 GTR substitution model Qseq for the evolution of unpaired nucleotides and a dinucleotide 16 × 16 GTR substitution model Qstruct.

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Open Data