Figure 3.

Evolutionary scenario for the DNA ligases of the NCLDV. The underlying species tree is the consensus of maximum-likelihood phylogenetic trees of 4 universal NCLDV genes (see text)[6]. Filled circles denote presence (in extant viruses) or acquisition (in ancestral forms) and empty circles denote absence or loss of the respective ligases (blue: NAD-dependent ligase, red: ATP-dependent ligase). Abbreviations: Canvi, Canarypox virus; FPV, Fowlpox virus; Goavi, Goatpox virus Pellor; Shevi, Sheeppox virus 17077-99; Lumsk, Lumpy skin disease virus NI-2490; Deevi, Deerpox virus W-848-83; Myxvi, Myxoma virus; Rabfi, Rabbit fibroma virus; MCV, Molluscum contagiosum virus; VV, Vaccinia virus; Varvi, Variola virus (smallpox virus); Orfvi, Orf virus; Bovpa, Bovine papular stomatitis virus; Swivi, Swinepox virus; Tanvi, Tanapox virus; Yabmo, Yaba monkey tumor virus; Yabdi, Yaba-like disease virus; Crovi, Crocodilepox virus; AMV, Amsacta moorei entomopoxvirus; MSV, Melanoplus sanguinipes entomopoxvirus; Helvi, Heliothis virescens ascovirus 3e; Trini, Trichoplusia ni ascovirus 2c; Spofr, Spodoptera frugiperda ascovirus 1a; ASFV, African swine fever virus; Aedta, Aedes taeniorhynchus iridescent virus (Invertebrate iridescent virus 3); CIV, Invertebrate iridescent virus 6; Lymdi, Lymphocystis disease virus 1; LDV, Lymphocystis disease virus - isolate China; ISKNV, Infectious spleen and kidney necrosis virus; SGV, Singapore grouper iridovirus; FV3, Frog virus 3; ATSV, Ambystoma tigrinum virus; Acapo, Acanthamoeba polyphaga mimivirus; Mamav, Mamavirus; ParAR, Paramecium bursaria Chlorella virus AR158; ParNY, Paramecium bursaria Chlorella virus NY2A; ParMT, Paramecium bursaria chlorella virus MT325; Acatu, Acanthocystis turfacea Chlorella virus 1; ParFR, Paramecium bursaria Chlorella virus FR483; PBCV, Paramecium bursaria Chlorella virus 1; EHV, Emiliania huxleyi virus 86; Felsp, Feldmannia species virus; ESV, Ectocarpus siliculosus virus 1; Ostvi, Ostreococcus virus OsV5; Marvi, Marseille virus.