Figure 4.

Predicted new families of antitoxins. A. Multiple alignment of COG2442 family domain, a predicted DNA-binding antitoxin protein of winged HTH motif superfamily. B. Multiple alignment of COG2886 family of predicted antitoxins containing the HTH domain. C. Multiple alignment of COG2880 family, an AbrB superfamily representative. Designations are the same as in Figure 2.