Homoplasy in genome-wide analysis of rare amino acid replacements: the molecular-evolutionary basis for Vavilov's law of homologous series

Igor B Rogozin¹ , Karen Thomson² , Miklós Csürös³ , Liran Carmel¹ and Eugene V Koonin¹

¹National Center for Biotechnology Information, National Library of Medicine, National Institutes of Health, Bethesda, MD 20894, USA

²Department of Computer Science, University of New Orleans, New Orleans, LA 70148, USA

³Department of Computer Science and Operations Research, Université de Montréal, Montréal, Québec H3C 3J7, Canada

author email corresponding author email

Biology Direct 2008, 3:7doi:10.1186/1745-6150-3-7


Published:	17 March 2008

Additional file 1:

Results of RGC_CAM analysis and estimates of homoplasy with sampling of outgroup species.

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Additional file 2:

Frequency of amino acid substitutions.

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Additional file 3:

Statistics of the comparisons of amino acid changes.

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Additional file 4:

Time estimates of the nematodes-insects-vertebrates divergence.

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