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Evidence from glycine transfer RNA of a frozen accident at the dawn of the genetic code

Harold S Bernhardt* and Warren P Tate

Biology Direct 2008, 3:53 doi:10.1186/1745-6150-3-53

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Hypothesis   Open Access

Primordial soup or vinaigrette: did the RNA world evolve at acidic pH?

Harold S Bernhardt, Warren P Tate Biology Direct 2012, 7:4 (20 January 2012)

Abstract | Provisional PDF | PubMed | Editor’s summary

The greater stability of key RNA bonds at acidic pH, such as link the phosphodiester backbone and between amino acids and tRNA, suggests the RNA world evolved in acidic conditions.

Hypothesis   Open Access

The transition from noncoded to coded protein synthesis: did coding mRNAs arise from stability-enhancing binding partners to tRNA?

Harold S Bernhardt, Warren P Tate Biology Direct 2010, 5:16 (9 April 2010)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central

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