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Resolution: standard / high Figure 3.
Linear dependence of domain-count changes on domain occurrence. Linear dependency of the fraction of domain-count changes on the domain-count itself.
Left panel : For each genome pair i the fraction
of domain-count changes that involve domains of category c is shown (vertical axis) as a function of the fraction of all domains in the genome that are associated with category c (horizontal axis) for the categories 'metabolic process' (blue), 'regulation of transcription'
(red), and 'protein kinase activity' (green). Each dot corresponds to the data for
one pair i of closely-related genomes. Both axes are shown on a logarithmic scale. The straight-lines
show least-squares fits of the form . The fitted slopes for the three categories are γprot.kin.activity = 0.56 ± 0.46, γreg.transcr. = 0.95 ± 0.20, and amet.proc. = 1.48 ± 0.31. For comparison the dotted lines show linear scaling. Right panel: A 99% posterior probability interval for the slope γc was estimated for all selected GO categories (Methods). The fitted slopes were ordered
from high to low and are shown in the right panel from left to right with the vertical
bars corresponding to the 99% posterior probability intervals for each slope γc. The slope γ = 1, corresponding to a linear dependency, is shown as a horizontal dotted line.
Molina and van Nimwegen Biology Direct 2008 3:51 doi:10.1186/1745-6150-3-51 |