Biology Direct

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Open Access Hypothesis

A new model defines the minimal set of polymorphism in HLA-DQ and -DR that determines susceptibility and resistance to autoimmune diabetes

Christian S Parry* and Bernard R Brooks

Author Affiliations

Computational Biophysics Section, Laboratory of Computational Biology, National Heart, Lung, and Blood Institute, National Institutes of Health, Bethesda, Maryland 20892-9314, USA

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Biology Direct 2008, 3:42 doi:10.1186/1745-6150-3-42

Published: 14 October 2008

Additional files

Additional file 1:

Parameters for nonlinear Poisson-Boltzmann calculations.

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Additional file 2:

HLA association with type 1 diabetes and incidence across populations according to the published literature.

Format: DOC Size: 86KB Download file

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Open Data