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Orphan SelD proteins and selenium-dependent molybdenum hydroxylases

Daniel H Haft email and William T Self email

Biology Direct 2008, 3:4doi:10.1186/1745-6150-3-4

Acknowledging an earlier observation of orphan SelD

Daniel Haft   (04 March 2008)  J. Craig Venter Institute email

Just after publication of our manuscript, we came across the following reference: Zhang Y, Romero H, Salinas G, Gladyshev VN., Dynamic evolution of selenocysteine utilization in bacteria: a balance between selenoprotein loss and evolution of selenocysteine from redox active cysteine residues. Genome Biol. 2006;7(10):R94. Epub 2006 Oct 20. We launched our study from the observation that SelD proteins explained by neither selenocysteine nor selenouridine pathways might imply a third SelD-dependent trait. The orphan status of SelD in Enterococcus faecalis and Haloarcula marismortui and possibility of SelD-dependence for selenium-dependent molybdenum hydroxylases were raised previously by Zhang, et al., and should have been cited as background to this paper. We regret having been unaware of this earlier observation.

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Acknowledged reference

Andrea Melendez   (10 March 2008)  BioMed Central

To access the above referenced article please click here.

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