This article is part of a series on Origin and early evolution of life, edited by Dr Eugene V Koonin. ResearchThe evolution of strand preference in simulated RNA replicators with strand displacement: Implications for the origin of transcriptionNobuto Takeuchi1 1 Theoretical Biology and Bioinformatics Group, Utrecht University, Padualaan 8, 3584 CH, Utrecht, The Netherlands 2 Department of Molecular Biology and Functional Genomics, Stockholm University, SE-10691, Stockholm, Sweden 3 School of Biological Sciences, University of Canterbury, Private Bag 4800, Christchurch, New Zealand
Biology Direct 2008, 3:33doi:10.1186/1745-6150-3-33
Additional filesAdditional file 1: 1 Figure 11. This figure shows the results of additional simulations where the decay rate of double-stranded molecules is reduced by a factor of 10 relative to that of single-stranded molecules. The figure is referred to in the Authors' response to Reviewer's report 3. 2 Figure 12. This figure shows the additional results that reveal a non-linear anti-correlation that evolves between kSP and kDP as a result of diverging selection under finite diffusion. This figure is referred to in the section, ''The effect of biases in the replication rates of single strands (a case where kSP ≠ kSM')". 3 The description of the ODE model with complex formation for a system of two replicator species. Format: PDF Size: 561KB Download file This file can be viewed with: Adobe Acrobat Reader |
|
|
|
 |   | Log on / register BioMed Central home | Journals A-Z | Feedback | Support | My details |
on Google Scholar
author email
corresponding author email|
|
| © 1999-2010 BioMed Central Ltd unless otherwise stated. Part of Springer Science+Business Media. |