Research
The evolution of strand preference in simulated RNA replicators with strand displacement: Implications for the origin of transcription
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* Corresponding author: Nobuto Takeuchi takeuchi.nobuto@gmail.com
1 Theoretical Biology and Bioinformatics Group, Utrecht University, Padualaan 8, 3584 CH, Utrecht, The Netherlands
2 Department of Molecular Biology and Functional Genomics, Stockholm University, SE-10691, Stockholm, Sweden
3 School of Biological Sciences, University of Canterbury, Private Bag 4800, Christchurch, New Zealand
Biology Direct 2008, 3:33 doi:10.1186/1745-6150-3-33
Published: 11 August 2008Additional files
Additional file 1:
1 Figure 11. This figure shows the results of additional simulations where the decay rate of double-stranded molecules is reduced by a factor of 10 relative to that of single-stranded molecules. The figure is referred to in the Authors' response to Reviewer's report 3.
2 Figure 12. This figure shows the additional results that reveal a non-linear anti-correlation that evolves between kSP and kDP as a result of diverging selection under finite diffusion. This figure is referred to in the section, ''The effect of biases in the replication rates of single strands (a case where kSP ≠ kSM')".
3 The description of the ODE model with complex formation for a system of two replicator species.
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