Biology Direct

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Open Access Research

Detection of co-eluted peptides using database search methods

Gelio Alves1, Aleksey Y Ogurtsov1, Siwei Kwok2, Wells W Wu3, Guanghui Wang3, Rong-Fong Shen3 and Yi-Kuo Yu1*

Author Affiliations

1 National Center for Biotechnology Information, National Library of Medicine, NIH, Bethesda, MD, 20894, USA

2 Department of Mathematics, University of Maryland, College Park, MD, 20742, USA

3 Proteomics Core Facility, National Heart, Lung, and Blood Institute, NIH, Bethesda, MD, 20892, USA

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Biology Direct 2008, 3:27 doi:10.1186/1745-6150-3-27

Published: 2 July 2008

Additional files

Additional file 1:

Supporting information for Detection of Co-eluted Peptides using Database Search Methods. ROC curves and cumulative ratio plots of X!Tandem, RAId_DbS and OMSSA from analyzing profile mode spectra generated by LTQ/FT, TOF/TOF and FT/FT instruments.

Format: PDF Size: 315KB Download file

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Additional file 2:

Profile co-identifiable-spectra. This file lists the spectra in the co-identifiable set. Each spectrum is listed with the true peptide identified and the standardized E-values by turning the quality scores reported by the five search methods into calibrated E-values [37].

Format: XLS Size: 191KB Download file

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Open Data