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N-glycan biosynthesis genes in human spermatogenesis data. |
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| σμ |
σwtrep |
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|
|
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| Gene Symbol |
RefSeq ID |
log2 FC |
p value |
log2 FC |
p value |
Gene Description |
|
|
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| B4GALT1 |
NM_001497 |
-0.45 |
0.499 |
-1.08 |
0.000 |
UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 1 |
| DDOST |
NM_005216 |
-2.22 |
0.067 |
-1.18 |
0.000 |
dolichyl-diphosphooligosaccharide-protein glycosyltransferase |
| DHDDS |
NM_024887 |
3.60 |
0.049 |
3.62 |
0.000 |
dehydrodolichyl diphosphate synthase |
| DPM1 |
NM_003859 |
-0.65 |
0.320 |
-1.06 |
0.000 |
dolichyl-phosphate mannosyltransferase polypeptide 1, catalytic subunit |
| GANAB |
NM_198334 |
1.45 |
0.045 |
2.12 |
0.000 |
glucosidase, alpha; neutral AB |
| MAN1A2 |
NM_006699 |
-1.27 |
0.019 |
-1.28 |
0.000 |
mannosidase, alpha, class 1A, member 2 |
| MAN2A2 |
NM_006122 |
-0.81 |
0.001 |
-1.06 |
0.000 |
mannosidase, alpha, class 2A, member 2 |
| UGCGL2 |
NM_020121 |
-0.97 |
0.003 |
-1.25 |
0.000 |
UDP-glucose ceramide glucosyltransferase-like 2 |
|
|
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| ALG2 |
NM_033087 |
-2.18 |
0.000 |
-2.20 |
0.000 |
asparagine-linked glycosylation 2 homolog (S. cerevisiae, alpha-1,3-mannosyltransferase) |
| ALG5 |
NM_013338 |
-1.90 |
0.000 |
-1.71 |
0.000 |
asparagine-linked glycosylation 5 homolog (S. cerevisiae, dolichyl-phosphate beta-glucosyltransferase) |
| ALG8 |
NM_024079 |
-1.36 |
0.001 |
-1.52 |
0.000 |
asparagine-linked glycosylation 8 homolog (S. cerevisiae, alpha-1,3-glucosyltransferase) |
| B4GALT2 |
NM_003780 |
2.33 |
0.006 |
2.29 |
0.000 |
UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 2 |
| MAN2A1 |
NM_002372 |
-1.21 |
0.055 |
-1.33 |
0.000 |
mannosidase, alpha, class 2A, member 1 |
| MGAT4A |
NM_012214 |
-1.84 |
0.001 |
-1.72 |
0.000 |
mannosyl (alpha-1,3-)-glycoprotein beta-1,4-N-acetylglucosaminyltransferase, isozyme A |
| OGT |
NM_181673 |
-2.31 |
0.009 |
-2.12 |
0.000 |
O-linked N-acetylglucosamine (GlcNAc) transferase (UDP-N-acetylglucosamine:polypeptide-N-acetylglucosaminyl transferase) |
| RPN1 |
NM_002950 |
-1.46 |
0.001 |
-1.51 |
0.000 |
ribophorin I |
| RPN2 |
NM_002951 |
-1.95 |
0.000 |
-2.00 |
0.000 |
ribophorin II |
|
The first, second and last column indicate the gene symbol, the RefSeq ID and the description of each N-glycan biosynthesis gene respectively. The third and fourth columns indicate the logarithm fold change and the P-value of each gene found by using σμ as the summary statistic. The fifth and sixth columns indicate the logarithm fold change and the P-value of each gene found by using σwtrep as the summary statistic. The cutoff criteria p ≤ 0.01 and |FC| ≥ 2 were applied. The first 8 genes are found to be statistically significant by σwtrep only, the rest was found with both statistics. | ||||||
Wong et al. Biology Direct 2008 3:23 doi:10.1186/1745-6150-3-23 |
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