Biology Direct

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Open Access Research

A novel superfamily containing the β-grasp fold involved in binding diverse soluble ligands

A Maxwell Burroughs1,2, S Balaji1, Lakshminarayan M Iyer1 and L Aravind1*

Author Affiliations

1 National Center for Biotechnology Information, National Library of Medicine, National Institutes of Health, Bethesda, MD 20894, USA

2 Bioinformatics Program, Boston University, Boston, MA 02215, USA

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Biology Direct 2007, 2:4 doi:10.1186/1745-6150-2-4

Published: 24 January 2007

Additional files

Additional file 1:

Cartoon representations of SLBB domains. File 1 contains cartoon representations of the transcobalamin and the Nqo1 middle domain showing the structural similarity and innovations associated with the potential binding site for soluble ligands.

Format: PDF Size: 266KB Download file

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Open Data

Additional file 2:

Comprehensive list of proteins of the SLBB superfamily, their gene neighborhoods, and domain architectures. Alignments of the SLBB domain will be submitted to the Pfam domain database [39].

Format: TXT Size: 820KB Download file

Open Data