Extensive parallelism in protein evolution
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* Corresponding author: Alexey S Kondrashov kondrash@umich.edu
Biology Direct 2007, 2:20 doi:10.1186/1745-6150-2-20
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Hypothesis
Occurrence of cancer at multiple sites: Towards distinguishing multigenesis from metastasis Wei-Kang Zhang, Chun Zhang, Jing J Zhang, Shi V Liu Biology Direct 2008, 3:14 (11 April 2008) |
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Research
Igor B Rogozin, Karen Thomson, Miklós Csürös, Liran Carmel, Eugene V Koonin Biology Direct 2008, 3:7 (17 March 2008) Homoplasy denotes the same (parallel) mutations occurring independently in different lineages. It is a scourge of phylogenetic methods. Here, however, it is shown that homoplasy is also an interesting evolutionary phenomenon. Homplasy seems, at least, in part, to underlie the so-called homologous series of phenotypic variation occurring in different, particularly, closely related lineages, an effect first described by the famous Russian geneticict Vavilov some 90 years ago.
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