On the origin of the translation system and the genetic code in the RNA world by means of natural selection, exaptation, and subfunctionalization
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* Corresponding author: Eugene V Koonin koonin@ncbi.nlm.nih.gov
Biology Direct 2007, 2:14 doi:10.1186/1745-6150-2-14
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Harold S Bernhardt, Warren P Tate Biology Direct 2010, 5:16 (9 April 2010) |
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Opinion
The fundamental units, processes and patterns of evolution, and the Tree of Life conundrum Eugene V Koonin, Yuri I Wolf Biology Direct 2009, 4:33 (29 September 2009) This article is part of a collection on Evolutionary Biology 150... A tree is a natural representation of evolution owing to the inherent tree-like character of the replication process but the fundamental units of evolution amenable to tree analysis seem to be individual genetic elements rather than complete genomes.
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Armen Y Mulkidjanian, Michael Y Galperin Biology Direct 2009, 4:27 (24 August 2009) The relatively high zinc content of living cells and its role as cofactor in many key enzymes and RNA structures might reflect the origin of life in zinc-rich environments.
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Hypothesis
Armen Y Mulkidjanian Biology Direct 2009, 4:26 (24 August 2009) Life may have emerged owing to the ability of porous, hydrothermal zinc sulfide precipitates to store solar energy and reduce atmospheric carbon dioxide, providing nourishment and shelter for the first organisms.
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Paul G Higgs Biology Direct 2009, 4:16 (24 April 2009) This article is part of a collection on Evolutionary Biology 150... |
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Andrei S Rodin, Eörs Szathmáry, Sergei N Rodin Biology Direct 2009, 4:4 (27 January 2009) This article is part of a collection on Origin and early evolution... The genetic code mediated in tRNAs by anticodons and the code embodied in tRNA acceptor stems responsible for correct tRNA aminoacylation have one common ancestor, originating even before translation.
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Evidence from glycine transfer RNA of a frozen accident at the dawn of the genetic code Harold S Bernhardt, Warren P Tate Biology Direct 2008, 3:53 (17 December 2008) This article is part of a collection on Origin and early evolution... We present evidence the first tRNA was specific for glycine, with an NCC anticodon derived from the 3'-CCA of a duplicated hairpin precursor, heralding the dawn of the genetic code.
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Review
Predicting the conformations of peptides and proteins in early evolution E James Milner-White, Michael J Russell Biology Direct 2008, 3:3 (28 January 2008) |
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Research
Artem S Novozhilov, Yuri I Wolf, Eugene V Koonin Biology Direct 2007, 2:24 (23 October 2007) |
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Eugene V Koonin Biology Direct 2007, 2:15 (31 May 2007) |