A putative RNA-interference-based immune system in prokaryotes: computational analysis of the predicted enzymatic machinery, functional analogies with eukaryotic RNAi, and hypothetical mechanisms of action

Viewing options:

Associated material:

Related literature:

Tools:

Post to:

Research

Kira S Makarova¹ , Nick V Grishin² , Svetlana A Shabalina¹ , Yuri I Wolf¹ and Eugene V Koonin¹

¹National Center for Biotechnology Information, National Library of Medicine, National Institutes of Health, Bethesda, MD 20894, USA

²Department of Biochemistry, University of Texas Southwestern Medical Center, 5323 Harry Hines Blvd, Dallas, TX 75390-9050, USA

author email corresponding author email

Biology Direct 2006, 1:7doi:10.1186/1745-6150-1-7


Published:	16 March 2006

Additional file 1:

GI number for all families of Cas proteins.

Format: XLS Size: 85KB Download file

This file can be viewed with: Microsoft Excel Viewer

Additional file 2:

multiple protein sequence alignment for COG1343.

Format: TXT Size: 22KB Download file

Additional file 3:

multiple protein sequence alignment for COG1857.

Format: TXT Size: 36KB Download file