Table 4

Hotspots non-randomly associated with non-synonymous sites in tumor suppressor genes according to the NSB test

Gene
Total number of codons
Number of non-synonymous hotspots

TP53
394
59
BRCA1
1864
12
BRCA2
3419
27
p16
157
1

The hotspots are listed in 3

Glazko et al. Biology Direct 2006 1:4   doi:10.1186/1745-6150-1-4