|
The NSMC and NSCS test results for BRCA1, BRCA2, and p16 genes |
||||
| Class ID |
Sites |
Mutations |
Hotspots |
P(H1)/χ2 |
|
|
||||
| BRCA1 |
||||
| Synonymous |
33 |
142 |
16 |
|
| Non-synonymous |
356 |
1842 |
170 |
0.204/0.006 |
| Nonsense |
141 |
704 |
74 |
0.079 |
| BRCA2 |
||||
| Synonymous |
55 |
103 |
20 |
|
| Non-synonymous |
797 |
4871 |
352 |
0.071/1.2 |
| Nonsense |
179 |
844 |
79 |
0.018 |
| p16 |
||||
| Synonymous |
40 |
63 |
13 |
|
| Non-synonymous |
171 |
321 |
65 |
0.388/0.423 |
| Nonsense |
18 |
162 |
14 |
0.070 |
|
The data for combined spectra from all tumor types are shown. Other designations are as in Table 1. | ||||
Glazko et al. Biology Direct 2006 1:4 doi:10.1186/1745-6150-1-4 |
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