Diverse bacterial genomes encode an operon of two genes, one of which is an unusual class-I release factor that potentially recognizes atypical mRNA signals other than normal stop codons

doi:10.1186/1745-6150-1-28

Biology Direct
Volume 1

Viewing options:

Associated material:

Readers' comments
PubMed record

Related literature:

Articles citing this article
on Google Scholar
on PubMed Central
Other articles by authors
on Google Scholar

Baranov PV
Vestergaard B
Hamelryck T
Gesteland RF
Nyborg J
Atkins JF

on PubMed

Baranov PV
Vestergaard B
Hamelryck T
Gesteland RF
Nyborg J
Atkins JF
Related articles/pages
on Google

on Google Scholar

on PubMed

Tools:

Post to:

Comments(1)

Class-I release factors lacking the domain 1.

Pavel Baranov (01 November 2006) University College Cork

This is a comment by an author who wish to mention recently published data relevant to this article.

A paper describing the complete genome of the bacterial endosymbiont Carsonella ruddii has been published in Science on the 13th of October (Nakabachi et al. 2006. Science 314:267). Apparently, the class-I release factors from this specie lack the domain 1. RF1 omits it entirely, while in RF2, if it exists, it is significantly truncated. This further underpins the idea discussed in this manuscript that the domain 1 is not obligatory in bacterial class-I RFs.

It is worth noticing that C. ruddii RFs have unusual “tripeptide anticodons”, PKS in RF1 and NPL in RF2.

Competing interests

none

top

Comments(1)

Diverse bacterial genomes encode an operon of two genes, one of which is an unusual class-I release factor that potentially recognizes atypical mRNA signals other than normal stop codons

Class-I release factors lacking the domain 1.

Have something to say? Post a comment on this article!