The origin of introns and their role in eukaryogenesis: a compromise solution to the introns-early versus introns-late debate?
-
Correspondence: Eugene V Koonin koonin@ncbi.nlm.nih.gov
Biology Direct 2006, 1:22 doi:10.1186/1745-6150-1-22
Accesses
- Last 30 days: 182 accesses
- Last year: 1937 accesses
- All time: 13387 accesses
Cited by
BioMed Central: 13 citations
|
Research
Energetics and genetics across the prokaryote-eukaryote divide Nick Lane Biology Direct 2011, 6:35 (30 June 2011) This article is part of a collection on Beyond the tree of life |
|
Review
The origin and early evolution of eukaryotes in the light of phylogenomics Eugene V Koonin Genome Biology 2010, 11:209 (5 May 2010) This article is part of a collection on 10th Anniversary... Comparative genomics and new phylogenies of eukaryote groups suggest a scenario in which the mitochondrial endosymbiosis triggered the origin of eukaryotes. |
|
Research article
Mark G Nielsen, Sudhindra R Gadagkar, Lisa Gutzwiller BMC Evolutionary Biology 2010, 10:113 (27 April 2010) |
|
Research article
Kristen S Swithers, Alireza G Senejani, Gregory P Fournier, J Peter Gogarten BMC Evolutionary Biology 2009, 9:303 (31 December 2009) Inteins and group I introns, but not spliceosomal or group II introns, are inserted into conserved, functionally active regions of host proteins and evade deletion by imposing functional constraints on the target site.
|
|
Research
Natalya Yutin, Eugene V Koonin Biology Direct 2009, 4:51 (18 December 2009) |
|
Research article
Multiple gains of spliceosomal introns in a superfamily of vertebrate protease inhibitor genes Hermann Ragg, Abhishek Kumar, Katharina Köster, Caterina Bentele, Yunjie Wang, Marc-André Frese, Natalie Prib, Olaf Krüger BMC Evolutionary Biology 2009, 9:208 (22 August 2009) |
|
Hypothesis
Exon definition as a potential negative force against intron losses in evolution Deng-Ke Niu Biology Direct 2008, 3:46 (13 November 2008) If the splicing of pre-mRNAs is initiated by exon definition, an exon larger than a particular size may cause splicing errors . Intron loss that results in oversized exons may thus be deleterious and selected against.
|
|
Research article
Patterns of intron gain and conservation in eukaryotic genes Liran Carmel, Igor B Rogozin, Yuri I Wolf, Eugene V Koonin BMC Evolutionary Biology 2007, 7:192 (12 October 2007) |
|
Hypothesis
The Biological Big Bang model for the major transitions in evolution Eugene V Koonin Biology Direct 2007, 2:21 (20 August 2007) |
|
Hypothesis
Protecting exons from deleterious R-loops: a potential advantage of having introns Deng-Ke Niu Biology Direct 2007, 2:11 (25 April 2007) |
|
Research
Conserved intron positions in ancient protein modules Albert DG de Roos Biology Direct 2007, 2:7 (8 February 2007) |
|
Hypothesis
Origin of phagotrophic eukaryotes as social cheaters in microbial biofilms Gáspár Jékely Biology Direct 2007, 2:3 (19 January 2007) |
|
Comment
Did group II intron proliferation in an endosymbiont-bearing archaeon create eukaryotes? Anthony M Poole Biology Direct 2006, 1:36 (7 December 2006) |