The orthology of HLA-E and H2-Qa1 is hidden by their concerted evolution with other MHC class I molecules

Etienne Joly and Virginie Rouillon

Equipe de Neuro-Immuno-Génétique Moléculaire, IPBS, UMR CNRS 5089, 205 route de Narbonne, 31077 Toulouse Cedex, France

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Biology Direct 2006, 1:2doi:10.1186/1745-6150-1-2


Published:	31 January 2006

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Additional File 1:

Comparison of primate α3 domains suggests past gene conversions rather than whole exon exchange. This figure is reproduced from Figure 1 in [38]. Areas boxed in red indicate zones where the HLA-E sequence matches better with HLA-Cw1, and in green with HLA-A3. Over the zones marked in blue, all six sequences are so homologous to one another that no grouping is suggested.

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