Table 3

Positive selection pressure in Treated and Untreated datasets


Selection pressure
Conditional selection pressure

Treated
+a
+
-
+a
+
Not + selected, or not present
Untreated
+
-b
+
+
Not + selected, or not present
+
Codon
12,13,19,33,35,37,41,57,60,62,63,6477,93 71c
10,24,30,54,73,74,82,90 53d
None
19, 63, 71 93e
10, 24, 30, 35, 48, 54, 73, 82, 88, 90
None

a positively selected. For selection pressure, Ka/Ks > 1 and LOD > 2; for conditional selection pressure, (Ka/Ks)Y|Xa > 1, (Ka/Ks)Y|X > 1, LOD > 3 and p < 0.001.

b negatively selected (Ka/Ks < 1 and LOD > 2)

c codon 71 is positively selected in Treated samples (Ka/Ks > 1 and LOD > 2), and it has a Ka/Ks value greater than 1 but a LOD score less than 2 in Untreated samples.

d codon 53 is positively selected in Treated samples (Ka/Ks > 1 and LOD > 2), and it has a Ka/Ks value less than 1 but a LOD score less than 2 in Untreated samples.

e In Treated dataset, codon 93 is positively selected with (Ka/Ks)Y|Xa > 1, (Ka/Ks)Y|X > 1, LOD > 3 but p > 0.001.

Chen and Lee Biology Direct 2006 1:14   doi:10.1186/1745-6150-1-14

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