Table 2

Significant differences of selection pressure between Treated and Untreated dataset
Position
 Treated
 Untreated
 p-value



Ka/Ks
 Na
 Ns
 LOD
 Ka/Ks
 Na
 Ns
 LOD
10a
 1.47
 516
 176
 5.4
 0.21
 172
 401
 71.57
 < 0.0001
11
 0.17
 15
 43
 10.38
 0.04
 7
 90
 35.47
 0.0017
17
 0.06
 17
 142
 49.46
 0.16
 55
 176
 40.54
 0.0006
19
 2.9
 183
 97
 17.72
 1.72
 278
 248
 9.45
 0.0004
20
 0.39
 137
 131
 12.56
 0.07
 41
 215
 80.54
 < 0.0001
23
 0.25
 27
 163
 14.25
 0.08
 11
 222
 35.57
 0.0006
24
 1.59
 85
 64
 2.49
 0.33
 22
 79
 6.73
 < 0.0001
30
 1.84
 211
 43
 4.1
 0.18
 22
 46
 12.11
 < 0.0001
32
 0.53
 49
 46
 3.08
 0.01
 2
 69
 31.72
 < 0.0001
48
 0.71
 72
 51
 1.62
 0.02
 3
 82
 36.4
 < 0.0001
50
 0.9
 27
 13
 0.51
 0.07
 2
 12
 5.74
 0.0007
53
 2.99
 48
 6
 2.44
 0.31
 5
 6
 1.91
 0.0032
54
 1.55
 246
 69
 3.25
 0.03
 7
 112
 50.03
 < 0.0001
58
 0.1
 46
 164
 53.2
 0.01
 3
 207
 113.48
 < 0.0001
61
 0.1
 55
 211
 70.15
 0.05
 63
 431
 172.9
 0.0031
62
 13.65
 419
 2
 8.93
 2.42
 446
 12
 3.38
 0.0094
63
 6.1
 1111
 91
 100.36
 3.23
 1343
 208
 71.62
 < 0.0001
66
 0.01
 12
 385
 181.09
 0.00
 1
 551
 286.44
 0.0002
67
 0.2
 64
 118
 26.07
 0.10
 75
 290
 95.99
 0.0002
71
 6.99
 601
 43
 58.9
 1.11
 195
 88
 0.63
 < 0.0001
73
 1.81
 130
 36
 3.17
 0.05
 5
 48
 18.6
 < 0.0001
74
 3.75
 75
 10
 5.36
 0.22
 7
 16
 4.09
 < 0.0001
76
 1.02
 34
 40
 0.28
 0.16
 10
 74
 11.25
 < 0.0001
77
 24.42
 635
 13
 91.3
 9.72
 700
 36
 79.13
 0.0025
82
 4.58
 339
 37
 25.9
 0.46
 51
 56
 4.77
 < 0.0001
83
 0.15
 18
 45
 13.27
 0.03
 10
 107
 49.35
 0.0006
84
 1.46
 112
 5
 0.56
 0.00
 0
 14
 300
 < 0.0001
85
 1.39
 48
 15
 0.79
 0.11
 3
 12
 5.01
 0.0001
88
 0.82
 154
 70
 1.11
 0.1
 25
 95
 32.49
 < 0.0001
90
 12.26
 472
 46
 107.02
 0.25
 12
 58
 6.9
 < 0.0001
92
 0.1
 34
 131
 44.36
 0.04
 25
 211
 90.47
 0.0044

a Mutations at codon in Italic are known associated with drug resistance. The nine codons that underwent a confident shift from positive selection in Treated to negative selection in Untreated are in bold.

Chen and Lee Biology Direct 2006 1:14   doi:10.1186/1745-6150-1-14